Lung Cancer Clinical Trials

NSCLC - Non-Small Cell Lung Cancer

Protocol Description Setting Population
ECOG 6508 A Phase II Study of L-BLP25 and Bevacizumab in Unresectable Stage IIIA and Stage IIIB Non-Squamous Non-Small Cell Lung Cancer After Definitive Chemoradaiation Chemo-naive Stage IIIA; Stage IIIB without significant pleural effusion
ECOG 5508 Randomized Phase III Study of Maintenance Therapy with Bevacizumab, Pemetrexed, or a Combination of Bevacizumab and Pemetrexed Following Carboplatin, Paclitaxel and Bevacizumab for Advanced Non-Squamous NSCLC Stage IV or IIIB with nodule in ipsilateral lobe no prior systemic chemotherapy for advanced stage lung cancer; adjuvant therapy allowed if >12 months since last dose

Boehringer 1200.167

A Phase IIIb, non-randomized, open-label, two-cohort study in patients with EGFR mutations-positive advanced adenocarcinoma of the lung, assessing the utility of the Afatinib Diarrhea Assessment and Mangement guidelines (ADAM)

Stage IIIB or IV

Epidermal Growth Factor Receptor (EGFR) mutation positive status; no more than one prior non-EGFR-TKI therapy

AdeptBio AB-OPN-0000608

Collection of plasma from subjects with non-small cell lung cancer (NSCLC)

Any Stage

Prior treatment with either gefitinib or erlotinib and have progressed

RTOG 0839

Randomized Phase II Study of Pre-operative Chemoradiotherapy +/- Panitumumab Followed by Consolidation Chemotherapy in Potentially Operable Locally Advanced NSCLC

Stage IIIA, N2+

Adenocarcinoma, Adenosquamous, large cell carcinoma, squamous carcinoma, non-lobular and non-diffuse bronchoalveolar cell carcinoma or NOS.

Questions

If you have any question on your eligibility for any of these trials or any general questions please feel free to contact our Clinical Research Coordinator at 773-665-9837(P), or fax at 773-665-6890.

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